Preface

Malignant mesothelioma is a malignant cancer sentinel. It's amazing how fast natural history with a median survival of 6 to 8 months, when untreated, is the environment related to such economic and social consequences that lawyers specialize in representing mesothelioma patients only. The experts to devote all his time to testify, and governments are forced to consider not only the prohibition of the environmental agent, but re-evaluate the entire compensation system for victims tort victims. Furthermore, its presence in some populations has changed the mentality of an entire community, such as Libby, Montana, Cappadocia, Turkey, and Sarnia Ontario.
          Because of their rarity, malignant mesothelioma is considered an orphan disease and managed anecdotally, in practice most of the cancer. However, this disease has created new scientific paradigm in the clinic, laboratory, and the community.
          This blog was created to correct the information of "disengagement" orphan disease and create awareness among scientists around the world on the new concepts of molecular genetics, epidemiology and carcinogenesis of mesothelioma. We, as editors and writers working to raise awareness about mesothelioma and reverse a disproportionately low number of R & D funding for the study of this type of cancer. We also believe that the study of this fascinating disease, occurring in the context of judicial matters must go through the same way that all science is in the path of discovery. Legal issues should have no effect, but, unfortunately, often in areas of science and medicine.
          In the past decade, evidence has accumulated that the cancer of mesothelioma caused by asbestos and erionite environmental carcinogens that interact with genetic predisposition, and viral infections during cardinogenesis. The result of these complex interactions determine which of exposed individuals develop cancer. On the other hand, mesothelioma has become an ideal model to study how genetic and viral infections, environmental impact of carcinogenesis, and to discover new targets for early diagnosis and therapy.
          Not only cancer caused as much controversy as mesothelioma. More than 40 years scientists have debated whether chrysotile asbestos causes mesothelioma or not. As if the dispute is not played enough chrysotile, new developments in the field of mesothelioma, where two of the editors of this blog (HP and Microsoft) reported that DNA tumor virus SV-40 that causes mesothelioma in animals, was present in some human mesothelioma. In addition to these important questions of causality, the conflict that exists regarding the best surgical treatment of diseases and the interpretation of the novel test for mesothelioma. All these issues volatile, even economic, legal, and most importantly, the scientific aspects discussed in various chapters of this blog. We recommend the reader not only to digest these issues, but they are the contradictions in mesothelioma promising as new data is entered.
          Distribution of specific knowledge of mesothelioma has led to an increase in the number of international conferences about mesothelioma, where scientists presented new and interesting results. Mesothelioma Asufficient number of specific research is strong and is no longer the stepchild of the meetings devoted to lung cancer and sarcoma. Doctors and scientists, as currently defined as a "mesothelioma expert", and advice to prevent and detect the disease early and to treat diseases that currently sought not only to other doctors, but a growing number of E- mail directly from patients and their families.
          The editors provided a complete text that describes the contradictions and facts in order to raise awareness about the epidemic of mesothelioma and how to help doctors and scientists in their efforts by the bank, or cure diseases or to develop new therapeutic options. The complexity of mesothelioma have only recently been implemented, and this complexity requires that the disease "graduate" from a chapter in the text of oncology. Therefore, this blog is intended to be used as an authoritative guide for doctors, primary care physicians, pulmonologists, medical oncologists, radiation oncologists and surgical oncologists as well as children in education in these straits. Moreover, due to the economy and the legal effects of mesothelioma, this blog will have a significant impact in the courts of general jurisdiction.
          It was a truly international effort, and North America, Europe, Middle East and Australia, the prospects for clinical and translational aspects of mesothelioma are presented. This fact in itself increases the overall character of the light of the epidemic, and emphasizes that the source of background information that could be expanded in future editions should be running at this time. The editors thank all the authors who took time from their busy schedules to contribute to this first attempt. His enthusiasm and patience in providing the latest information about their areas of expertise are reflected in their chapters and the editors hope their efforts will be rewarded with a new generation of oncologists and researchers who will be treated with knowledge of mesothelioma rather than apathy. Finally, the editors want to thank for the fact that the foresight to recognize the Springer gap in the literature about mesothelioma, the publication of this blog. As he approached the first editor of this project, there was no indication the market is too small or the population in favor or supporting the project, and Springer was the genuine colleague in this endeavor. Special thanks to Beth Campbell, Stephanie Saxon, Chernov Barbara, Brian and Laura Gillan Drozda diZerega, all of which was this effort with the unconditional support.